Induction of Labor Basics: Medications, Balloons, Amniotomies…Oh My!

Starting your OB/GYN residency? Or just trying to wrap your head around labor induction? Let’s break it all down in a way that’s easy to understand—and clinically useful.

Before we dive in, if you’re a fourth-year med student who just matched into OB/GYN, I’ve created a free resource just for you:

The OB/GYN Residency Starter Pack: A 5-Step Guide for Incoming Interns

It’s designed to help you feel more prepared and less overwhelmed before day one. Download it here to get your copy.

What is Induction of Labor?

Induction of labor means stimulating uterine contractions before spontaneous labor begins. Why do we do this? When the benefits of delivery outweigh the risks of continuing the pregnancy (or electively after 39w0d).

To review the common indications, check out ACOG Practice Bulletin #831: Medically Indicated Late Preterm and Early Term Deliveries.

The Two Phases of Induction

Induction can be thought of in two phases:

Phase 1: Cervical Ripening

The goal here is to soften, thin, and slightly dilate the cervix to prepare it for effective contractions.

We use the Bishop Score to assess how “favourable” the cervix is. It evaluates:

  • Dilation

  • Effacement

  • Station

  • Position

  • Consistency

There’s no universally agreed-upon “favorable” score—some studies use 6, others use 8—but generally, a score between 6–8 means the cervix is ready for Phase 2.

Phase 2: Induction of Labor

Once the cervix is favourable, we move to actually initiating labor  with medications or procedures to start or strengthen contractions.

Phase 1: Cervical Ripening 

Medical Methods

  • Misoprostol (Cytotec)

    • Synthetic prostaglandin E1

    • Administered orally, sublingually, or vaginally

  • Dinoprostone (Cervidil)

    • Synthetic prostaglandin E2

    • Vaginal insert or gel

Mechanical Methods

  • Single or Double Balloon Catheters (Foley or Cook)

    • Inserted through the cervix and inflated

    • Generally requires at least fingertip dilation

    • Can be combined with medication

  • Osmotic Dilators (Laminaria, Dilapan-S)

    • Expand in the cervical canal over time

  • Extra-Amniotic Saline Infusion (EASI)

    • Infuses saline between uterus and membranes

  • Membrane Stripping

    • Technically an induction method, but often done during ripening if cervix is dilated enough

Common Clinical Approach:

  • Start with misoprostol every 3-6 hours

  • Once patient reaches ~1 cm dilation, place a Foley or Cook balloon (and strip membranes if possible)

  • Balloon falls out at ~3–4 cm → move to Phase 2

Phase 2: Inducing Labor

Medical Methods

  • Oxytocin (Pitocin)

    • IV infusion

    • Generally titrated every 30 minutes

    • Goal: 5 contractions in 10 minutes or adequate MVUs if using an IUPC

Mechanical Methods

  • Amniotomy (Artificial Rupture of Membranes)

    • No strict rules about timing

    • Early amniotomy may shorten labor without increasing cesarean risk in patients with a favourable cervix

  • Nipple Stimulation

    • Not commonly used in hospitals

    • Mostly studied in low-risk pregnancies

Fun fact: One of my patients once nipple-stimmed her way from closed to 4 cm because she declined all other interventions!

Induction Scenarios (Clinical Examples)

1. G1P0, Induction for Preeclampsia Without Severe Features

  • Closed cervix → 4 vaginal misoprostol doses

  • Foley + membrane strip at 1 cm

  • Foley falls out → Bishop score 6

  • Pitocin + amniotomy → vaginal delivery

2. G4P3003, Induction for Advanced Maternal Age

  • Initial exam: 2/50/-3 → Foley + misoprostol

  • Balloon falls out → Bishop 5

  • Another miso dose → Bishop 7

  • Pitocin started → SROM → delivery

Anecdotal tip: Multiparous patients often don’t need perfect Bishop scores to respond to Pitocin + amniotomy!

3. G2P0101, Elective Term Induction

  • Closed cervix → Cervidil for 12 hours

  • 1.5/20/-3 → Balloon + oral miso

  • Balloon falls out → Bishop 6

  • Amniotomy → contractions slow → Pitocin started → delivery

Key Takeaways

  • Induction = 2 phases: ripening (Phase 1) and actual induction (Phase 2)

  • Medical methods: misoprostol, dinoprostone, oxytocin

  • Mechanical methods: balloons, amniotomy

  • Bishop Score is your guide to timing and transition

  • Start with cervical ripening if cervix is unfavourable

  • Use Pitocin and/or amniotomy once favourable

    Don’t forget to grab your free OB/GYN Residency Starter Pack—a 5-step guide to help you prepare before July 1.
    Download it here

References

https://www.acog.org/clinical/clinical-guidance/practice-bulletin/articles/2009/08/induction-of-labor

https://www.acog.org/clinical/clinical-guidance/committee-opinion/articles/2021/07/medically-indicated-late-preterm-and-early-term-deliveries

https://www.ajog.org/article/S0002-9378(19)30964-0/abstract

https://pubmed.ncbi.nlm.nih.gov/16885669/

https://pubmed.ncbi.nlm.nih.gov/18515515/

https://pubmed.ncbi.nlm.nih.gov/20927722/

https://pubmed.ncbi.nlm.nih.gov/11687101/

https://pubmed.ncbi.nlm.nih.gov/15674873/

https://www.ajog.org/article/s0002-9378(14)00055-6/fulltext

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Vaginal Delivery Basics: A Step-by-Step Tutorial for Your First Delivery

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